Augmentation of Spinal Fusion with a Demineralized Bone/hyaluronan Matrix
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چکیده
INTRODUCTION Autogenous iliac crest bone graft continues to be the material of choice for posterolateral lumbar intertransverse process spine fusion. However, continued interest lies in developing bone graft alternatives that can be used as either graft extenders, graft enhancers, or graft substitutes. It was the purpose of this study to evaluate the efficacy of a demineralized bone matrix/ hyaluronan formulation as a bone graft enhancer to autograft in rabbit posterolateral spine fusion. For this study, we chose to use an established bone paucity model of posterolateral spine fusion (1).
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Prospective Comparison of Commercially Available Demineralized Bone Matrix for Spinal Fusion
INTRODUCTION: Demineralized bone matrix derived from human tissues has demonstrated the ability to aid in the stimulation of an osteoinductive response allowing for improved bone growth and fusion. In an effort to augment the available grafting material as well as increase fusion rates, the utilization of a demineralized bone matrix (DBM) as a graft extender or even as a graft substitute has be...
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Spinal fusion is a gold-standard treatment for many disorders of the spine with autogenous bone graft as the gold-standard source for augmenting fusion. However, the morbidity and limitations of autogenous bone grafting has motivated the search for bone graft alternatives. One such alternative is demineralized bone matrix (DBM). The purpose of this paper is to describe and characterize the prop...
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BACKGROUND Although autogenous iliac bone graft (AIBG) remains the gold standard for spine fusion, harvesting morbidity has prompted the search for alternatives especially for multi-segment fusion. This study aimed to evaluate the efficacy of using demineralized bone matrix (DBM) as a substitute of AIBG for long instrumented posterolateral fusion (≧ three-level fusion). METHODS A total of 47 ...
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